Volume 25 Supplementary Issue 3

Unraveling the Diverse Clinical Progression of Subcutaneous Fat Necrosis in Neonates

Ramya Obbai Manohar, Vani Hebbal Nagarajappa, Shamkiran, Relangi Lakshmi Deepika

Abstract

Subcutaneous fat necrosis of newborn (SFNN) is a rare benign panniculitis commonly seen in term and post-term neonates. The condition is characterized by the development of subcutaneous nodules. Usually, these nodules have an uncomplicated course, but they require constant monitoring, as they can be worsened by metabolic abnormalities such as hypercalcemia. The skin nodules predominantly appear within the first 4 weeks of life and tend to resolve in about 12 weeks from onset; however, in rare instances, it may take much longer for complete recovery.

We present 3 cases of SFNN, among which 1 neonate had an unusually stormy clinical course lasting for 10 months. In contrast, the other 2 neonates showed improvement in 2 to 4 weeks. The prolonged clinical course and the extensive skin lesions in 1 neonate warranted treatment for a longer duration to prevent recurring hypercalcemia, and this prompted us to publish this series.

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